2. GPCR/G Protein Neuronal Signaling
  3. Cholecystokinin Receptor
  4. BBL454

BBL454 (Compound 43) is a Cholecystokinin 2B (CCK2B) receptor agonist. BBL454 induces hyperactivity and improves memory in rat models while it has weak activity on the peripheral CCK2 receptor and no anxiogenic activity. BBL454 increases gastric acid output in anesthetised rat models. BBL454 can be used for diabetes research.

For research use only. We do not sell to patients.

BBL454

BBL454 Chemical Structure

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BBL454 Related Antibodies

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CCKAR CCKBR

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Description

BBL454 (Compound 43) is a Cholecystokinin 2B (CCK2B) receptor agonist. BBL454 induces hyperactivity and improves memory in rat models while it has weak activity on the peripheral CCK2 receptor and no anxiogenic activity. BBL454 increases gastric acid output in anesthetised rat models. BBL454 can be used for diabetes research[1][2].

IC50 & Target[1]

CCKBR

 

Molecular Weight

746.89

Formula

C40H54N6O8
SMILES

CCCCCCC(CC(N[C@@H](CC1=CNC2=C1C=CC=C2)C(N(C)[C@@H](CCCC)C(N[C@@H](CC(O)=O)C(N[C@@H](CC3=CC=CC=C3)C(N)=O)=O)=O)=O)=O)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BBL454 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BBL454BBL 454BBL-454Cholecystokinin ReceptorCCK ReceptorCCK2BHyperactivityMemoryGastric acidDiabetesInhibitorinhibitorinhibit

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