Aselacin A

Cat. No.: HY-N5170: FAQs
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Aselacin A targets endothelin-1 receptor (ET-1 receptor), inhibits the the binding of ET-1 to ETA receptor and ETB receptor. Aselacin A inhibits the ET-1 binding to bovine atrial membrane and porcine cerebral membrane with IC₅₀ of 22 μg/mL and 20 μg/mL. Aselacin A can be used for research of cardiovascular diseases.

For research use only. We do not sell to patients.

Aselacin A Chemical Structure

CAS No. : 156223-06-2

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ET_A ET_B

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Description	Aselacin A targets endothelin-1 receptor (ET-1 receptor), inhibits the the binding of ET-1 to ETA receptor and ETB receptor. Aselacin A inhibits the ET-1 binding to bovine atrial membrane and porcine cerebral membrane with IC₅₀ of 22 μg/mL and 20 μg/mL. Aselacin A can be used for research of cardiovascular diseases^[1].
Molecular Weight	909.08
Formula	C₄₆H₆₈N₈O₁₁
CAS No.	156223-06-2
SMILES	O=C1O[C@@H]([C@@H](C(NCCC(N[C@H](CC2=CNC3=C2C=CC=C3)C(N[C@H](CO)C(NC1)=O)=O)=O)=O)NC([C@@H](CCC(N)=O)NC(CCCCCCCC(/C=C/C=C/CCCCC)O)=O)=O)C
Structure Classification	Others
Initial Source	Microorganisms fungi AB 2093T-194 and AB 2086L-51
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (265 KB) Handling Instructions (2659 KB)
References	[1]. Jackson M, et al., Aselacins, novel compounds that inhibit binding of endothelin to its receptor. I. The producing organism, fermentation and biological activity. J Antibiot (Tokyo). 1994 May;47(5):523-7. [Content Brief]

Aselacin A Related Classifications

Cardiovascular Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aselacin A156223-06-2Endothelin ReceptorInhibitorinhibitorinhibit

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Aselacin A

Aselacin A Related Antibodies

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