2. Apoptosis Immunology/Inflammation
  3. Apoptosis Interleukin Related
  4. Apoptosis inducer 42

Apoptosis inducer 42 is an apoptosis inducer. Apoptosis inducer 42 activates late apoptosis and inhibits IL-6 secretion. Apoptosis inducer 42 shows high cytotoxicity towards cancer cells. Apoptosis inducer 42 can be used for cancer research, such as colon cancer.

For research use only. We do not sell to patients.

Apoptosis inducer 42

Apoptosis inducer 42 Chemical Structure

CAS No. : 66685-93-6

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Apoptosis inducer 42 Related Antibodies

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Description

Apoptosis inducer 42 is an apoptosis inducer. Apoptosis inducer 42 activates late apoptosis and inhibits IL-6 secretion. Apoptosis inducer 42 shows high cytotoxicity towards cancer cells. Apoptosis inducer 42 can be used for cancer research, such as colon cancer[1].

IC50 & Target[1]

IL-6

 

In Vitro

Apoptosis inducer 42 (Compound 11) inhibits SW480, SW620, PC3f, HCT116 and HaCaT cells growth with IC50 values of 5.1, 6.3,6.0, 4.4 and 14.2 μM, respectively[1].
Apoptosis inducer 42 (4.4-6.3 μM, 72 h) reduces the amount of live cells in SW480, SW620, PC3f and HCT116 cells[1].
Apoptosis inducer 42 (4.4-6.3 μM, 72 h) activates late apoptosis and inhibits IL-6 secretion in SW480, SW620, PC3f and HCT116 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis inducer 42 Related Antibodies

Apoptosis Analysis[1]

Cell Line: SW480, SW620, PC3f and HCT116 cells
Concentration: 5.1 μM in SW480, 6.3 μM in SW620, 6.0 μM in PC3f, 4.4 μM in HCT116 cells
Incubation Time: 72 h
Result: Activated >80% late apoptosis.
Molecular Weight

224.26

Formula

C11H13OPS
CAS No.
SMILES

O=C1CCP(C2=CC=CC=C2)(CC1)=S
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Apoptosis inducer 42 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Apoptosis inducer 4266685-93-6Apoptosis inducer42Apoptosis inducer-42ApoptosisInterleukin RelatedILIL-6SW480SW620PC3fHCT116Inhibitorinhibitorinhibit

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