TRIM29 Antibody (YA4260)

Cat. No.: HY-P84563: Data Sheet User Guide for Antibodies
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TRIM29 Antibody (YA4260) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to TRIM29.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
Technical Parameters
Properties
Documentation

Description	TRIM29 Antibody (YA4260) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to TRIM29.
Background	TRIM29 plays a pivotal role in regulating macrophage activation during viral or bacterial infections in the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in lysosomes to induce its Lys-48 ubiquitination and subsequent degradation, thereby suppressing type I interferon expression and pro-inflammatory cytokine production. By a similar mechanism, TRIM29 also induces Lys-48 ubiquitination of STING1, leading to its degradation.
Gene ID	23650 [NCBI]
SwissProt ID	Q14134
Synonyms	ATDC
Molecular Weight	Predicted band size: 66 kDa; Observed band size: 66 kDa
Purity	affinity purified.
Conjugation	Non-conjugated
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Clonality	Monoclonal Antibody
Host	Mouse
Reactivity	Human
Dilution Ratio	WB: 1/500-1/2000; IF: 1/100-1/500; FC: 1/200-1/400; ELISA: 1/10000
Application	WB, ICC/IF, FC, ELISA
Appearance	Liquid
Formulation	Supplied in PBS with 0.05% sodium azide
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG2a
Immunogen	Purified recombinant fragment of human TRIM29 (AA: 451-588) expressed in E. Coli.
Documentation	Data Sheet (234 KB) User Guide for Antibodies (1077 KB)

TRIM29 Antibody (YA4260) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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TRIM29 Antibody (YA4260)

Biological Activity

Technical Parameters

Properties

Documentation

TRIM29 Antibody (YA4260) Related Classifications

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