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  4. TIMP2 Antibody (YA034)

TIMP2 Antibody (YA034) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TIMP2.

For research use only. We do not sell to patients.

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10 μL In-stock
50 μL In-stock
100 μL In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products

Publications Citing Use of MCE TIMP2 Antibody (YA034)

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

TIMP2 Antibody (YA034) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TIMP2.

Background

TIMP2 is a tissue inhibitor of metalloproteinases that forms complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. It is known to act on various matrix metalloproteinases including MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16, and MMP-19.

Tag

Free

Gene ID
SwissProt ID
Synonyms
Metalloproteinase inhibitor 2 precursor; Tissue inhibitor of metalloproteinases 2; Collagenase inhibitor; CSC 21K; CSC21K; TIMP2; TIMP 2; TIMP 2; TIMP metallopeptidase inhibitor 2; TIMP2_HUMAN; Metalloproteinase inhibitor 2; CSC-21K; TIMP-2.
Molecular Weight

Predicted band size: 24 kDa; Observed band size: 24 kDa

Purity

Protein A affinity purified.

Subcellular Location

Secreted.

Conjugation

Non-conjugated

Modification

Unmodified

RRID
Research Field

Cardiovascular

Product Categories

Primary Antibody; Mouse Monoclonal Antibody

Clonality

Monoclonal

Host

Mouse

Reactivity

Human

Dilution Ratio

WB: 1:500-2000;IHC-P: 1:20-100;Flow-Cyt: 1:25;

  • Western blot analysis of extracts from M-brain (lane 1) and M-lung (lane 2) using TIMP2 antibody. Proteins were transferred to a PVDF membrane and blocked with 5% nonfat powdered milk in PBST for 2 hour at room temperature. The primary antibody (1/1000) and loading control antibody (GAPDH, 1/3000) was diluted with 5% nonfat powdered milk in PBST at 4°C overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/8,000) was incubated for 45min at room temperature.
Application

WB, IHC-P, FC

Appearance

Liquid

Formulation

Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG1

Sensitivity

Endogenous

Immunogen

KLH conjugated synthetic peptide derived from human TIMP-2.

Database
Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
TIMP2 Antibody (YA034)
Cat. No.:
HY-P80356
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