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  2. Primary Antibodies
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  4. Thyroglobulin Antibody (YA5696)

Thyroglobulin Antibody (YA5696)

Cat. No.: HY-P86004
User Guide for Antibodies Technical Support

Thyroglobulin Antibody (YA5696) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Thyroglobulin. It can be applicated for IHC-P, ELISA assays, in the background of human.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Thyroglobulin Antibody (YA5696) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Thyroglobulin. It can be applicated for IHC-P, ELISA assays, in the background of human.

Background

Thyroglobulin (TG) serves as a substrate for the synthesis of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The production involves iodination of specific tyrosine residues in TG followed by oxidative coupling within the thyroid follicle lumen (by similar PubMed:17532758, PubMed:32025030). After re-internalization of TG, lysosomal proteolysis releases T3 and T4 from the polypeptide backbone for secretion into the bloodstream (by similar PubMed:32025030). One TG dimer generates 7 thyroid hormone molecules (by similar PubMed:32025030).

Gene ID
SwissProt ID
Synonyms
Thyroglobulin; Tg;
Molecular Weight

Predicted band size: 305 kDa;

Purity

affinity chromatography.

Conjugation

Non-conjugated

Modification

Unmodified

Product Categories

Primary Antibody; Mouse Monoclonal Antibody

Clonality

Monoclonal

Host

Mouse

Reactivity

Human

Dilution Ratio

IHC: 1:200-400; ELISA: 1:500-5000

Application

IHC-P, ELISA

Appearance

Liquid

Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG1

Immunogen

Synthesized peptide derived from human Thyroglobulin AA range: 2700-2768

Documentation

Thyroglobulin Antibody (YA5696) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Thyroglobulin Antibody (YA5696)
Cat. No.:
HY-P86004
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