SPINK1 Antibody (YA1204)

SPINK1 Antibody (YA1204) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1204), targeting SPINK1. SPINK1 Antibody (YA1204) can be used for IHC-P experiment in human background.

SPINK1, a serine protease inhibitor, functions as an anti-trypsin agent, exhibiting inhibitory activity against trypsin. Particularly crucial in the pancreas, SPINK1 serves as a protective factor preventing the premature activation of zymogens catalyzed by trypsin. Beyond its pancreatic role, SPINK1 plays a distinctive function in the male reproductive tract, where it binds to sperm heads. In this context, it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production. These diverse roles highlight the significance of SPINK1 in regulating proteolytic activity and contributing to the protective mechanisms in both the pancreas and male reproductive processes.

P00995

Predicted band size: 9 kDa; Observed band size: 9 kDa

Affinity Purified

Non-conjugated

Unmodified

AB_3103127

Cell Biology

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

IHC: 1/100-1/200

IHC-P

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.35.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

Recombinant protein of human SPINK1