SOX10 Antibody (YA5581)

SOX10 Antibody (YA5581) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SOX10. It can be applicated for WB, ICC/IF, ELISA assays, in the background of human, mouse, rat.

SOX10 is a transcription factor that plays a central role in developing and mature glia (By similarity). It specifically activates the expression of myelin genes, such as DUSP15 and MYRF, during oligodendrocyte (OL) maturation, thereby playing a key role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). It acts as a transcriptional activator of MITF, synergistically with PAX3 (PubMed:21965087). Additionally, it transcriptionally activates MBP by binding to the gene promoter (By similarity).

P56693

Predicted band size: 49 kDa; Observed band size: 60 kDa

Protein G

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human, Mouse, Rat

WB: 1:500-2000; ICC/IF: 1:100-500; ELISA: 1:1000-5000

WB, ICC/IF, ELISA

Liquid

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Synthesized peptide derived from human protein AA range:1-100