SCD1 Antibody (YA1163)

SCD1 Antibody (YA1163) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SCD1.

SCD1 (Stearoyl-CoA desaturase 1) is a crucial enzyme utilizing O(2) and electrons from reduced cytochrome b5 to catalyze the introduction of the first double bond into saturated fatty acyl-CoA substrates, including palmitoyl-CoA and stearoyl-CoA. This process results in the production of a mixture of 16:1 and 18:1 unsaturated fatty acids, playing a pivotal role in lipid biosynthesis. SCD1 plays a key role in regulating the expression of genes involved in lipogenesis and mitochondrial fatty acid oxidation, contributing to the biosynthesis of membrane phospholipids, cholesterol esters, and triglycerides. Additionally, SCD1 is indispensable for normal development of sebaceous glands and the biosynthesis of Delta-9 unsaturated fatty acids in the Harderian gland. It is also required for the production of meibum, an oily substance crucial for preventing the drying of the cornea, emphasizing its diverse and essential roles in cellular processes and tissue development.

O00767

Predicted band size: 41 kDa; Observed band size: 37 kDa

Affinity Purified

Non-conjugated

Unmodified

AB_3103533

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

IHC: 1:100-1:200

IHC-P

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.14.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

Recombinant protein of human SCD1