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  4. Monoclonal Antibodies Recombinant Antibodies
  5. RelB Antibody (YA1852)

RelB Antibody (YA1852) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RelB.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

RelB Antibody (YA1852) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RelB.
Background

RelB is a pleiotropic transcription factor belonging to the Rel-like domain protein family, forming NF-kappa-B heterodimers (e.g., RelB-p50 and RelB-p52) that function as transcriptional activators by binding to kappa-B sites in target gene DNA, regulating processes like inflammation, immunity, and cell differentiation. RelB does not directly associate with DNA, RELA/p65, or REL but stimulates promoter activity in the presence of NFKB2/p49. As part of the NUPR1/RELB/IER3 survival pathway, RelB may confer remarkable resistance to cell stress (e.g., starvation or gemcitabine treatment) in pancreatic ductal adenocarcinoma. Additionally, RelB represses the transcriptional activity of the CLOCK-BMAL1 heterodimer independently of CRY1/CRY2, with enhanced repression observed with NFKB2/p52. RelB is essential for the maturation and function of T and B lymphocytes.
Gene ID
SwissProt ID
Synonyms
RELB; Transcription factor RelB; I-Rel
Molecular Weight

Predicted band size: 62 kDa; Observed band size: 62 kDa
Purity

Affinity Purified
Conjugation

Non-conjugated
Modification

Unmodified
Research Field

Cell Biology
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Mouse, Rat
Dilution Ratio

WB: 1/500-1/1000;IP: 1/20
Application

WB, IP
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

A synthetic peptide of human Rel B
Database

Entrez Gene: 5971 Human ; 19698 Mouse ; 100360982 Rat

SwissProt: Q01201 Human ; Q04863 Mouse ;

OMIM: 617585 Human

Documentation
User Guide for Antibodies (1077 KB)

RelB Antibody (YA1852) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
RelB Antibody (YA1852)
Cat. No.:
HY-P82107
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