Rab 5A Antibody (YA6233)

Rab 5A Antibody (YA6233) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Rab 5A. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

Rab 5A, a member of the small GTPases Rab family, is a key regulator of intracellular membrane trafficking, governing processes from vesicle formation to membrane fusion. It cycles between inactive GDP-bound and active GTP-bound states, with the latter recruiting downstream effectors to directly orchestrate vesicle formation, movement, tethering, and fusion. RAB5A is essential for plasma membrane-early endosome fusion and modulates filopodia extension. It also facilitates the exosomal release of SDCBP, CD63, PDCD6IP, and syndecan. By similarity, Rab 5A likely regulates apoptotic cell-containing phagosome maturation downstream of DYN2 and PIK3C3.

P20339

Predicted band size: 24 kDa; Observed band size: 24 kDa

Protein A

Non-conjugated

Unmodified

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Monoclonal

Rabbit

Human, Mouse, Rat

IHC: 1:1000-1:4000; WB: 1:1000-1:5000; ICC/IF: 1:200-1:1000; ELISA: 1:5000-1:20000; IP: 1:50-1:200,

WB, IHC-P, ICC/IF, IP, ELISA

Liquid

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG