1. Antibodies
  2. Primary Antibodies
  3. Polyclonal Antibodies
  4. PSMB1 Antibody

PSMB1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 26 kDa, targeting to PSMB1. It can be used for WB, IF-Cell, IHC-P, FC assays with tag free, in the background of Human,Mouse, Rat.

For research use only. We do not sell to patients.

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

PSMB1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 26 kDa, targeting to PSMB1. It can be used for WB, IF-Cell, IHC-P, FC assays with tag free, in the background of Human,Mouse, Rat.

Background

PSMB1 is a non-catalytic component of the 20S core proteasome complex, involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. When associated with two 19S regulatory particles, it forms the 26S proteasome, participating in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in maintaining protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, as well as proteins whose functions are no longer required. When associated with PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation, which is required in pathways such as spermatogenesis (20S-PA200 complex) or the generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).

Gene ID
SwissProt ID
Synonyms
FLJ25321 antibody; HC5 antibody; KIAA1838 antibody; Macropain subunit C5 antibody; Multicatalytic endopeptidase complex subunit C5 antibody; Proteasome (prosome macropain) subunit beta type 1 antibody; Proteasome beta 1 subunit antibody; Proteasome component C5 antibody; Proteasome gamma chain antibody; Proteasome subunit beta type 1 antibody; Proteasome subunit beta type-1 antibody; Proteasome subunit HC5 antibody; PSB1_HUMAN antibody; PSC5 antibody; PSMB 1 antibody; PSMB1 antibody
Molecular Weight

Predicted band size: 26 kDa; Observed band size: 24 kDa

Purity

affinity purified

Subcellular Location

Cytoplasm, Nucleus.

Conjugation

Non-conjugated

Modification

Unmodified

RRID
Product Categories

Primary Antibody; Rabbit Polyclonal Antibody

Clonality

Polyclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

Dilution Ratio

WB: 1:2,000;IF-Cell: 1:500;IHC-P: 1:5,000;FC: 1:1,000

Application

WB, IHC-P, ICC/IF, FC

Positive Control

293T cell lysate, HeLa cell lysate, K-562 cell lysate, MCF7 cell lysate, NIH/3T3 cell lysate, Mouse brain tissue lysate, Rat brain tissue lysate, HeLa, human kidney tissue,

Appearance

Liquid

Formulation

Supplied in phosphate buffered saline (pH 7.4), 150 mM NaCl and 50% glycerol. Preservative: 0.02% sodium azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Immunogen

Recombinant protein within Human PSMB1 aa 29-241.

Database
Documentation

PSMB1 Antibody Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PSMB1 Antibody
Cat. No.:
HY-P83718
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