2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. PIP5K1C Antibody (YA1644)

PIP5K1C Antibody (YA1644)

Cat. No.: HY-P81899
User Guide for Antibodies Technical Support

PIP5K1C Antibody (YA1644) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1644), targeting PIP5K1C, with a predicted molecular weight of 72 kDa (observed band size: 90,87 kDa). PIP5K1C Antibody (YA1644) can be used for WB, IP experiment in human, mouse background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

PIP5K1C Antibody (YA1644) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1644), targeting PIP5K1C, with a predicted molecular weight of 72 kDa (observed band size: 90,87 kDa). PIP5K1C Antibody (YA1644) can be used for WB, IP experiment in human, mouse background.
Background

PIP5K1C is a kinase that catalyzes the phosphorylation of phosphatidylinositol 4-phosphate (PtdIns(4)P/PI4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2/PIP2), a lipid second messenger regulating cellular processes such as signal transduction, vesicle trafficking, actin cytoskeleton dynamics, cell adhesion, and motility. PtdIns(4,5)P2 can act directly as a second messenger or serve as a precursor for other messengers, including inositol 1,4,5-trisphosphate (IP3), diacylglycerol (DAG), or phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3/PIP3) (by similarity). PIP5K1A-mediated phosphorylation of PtdIns(4)P is the primary pathway for PtdIns(4,5)P2 synthesis (by similarity). Along with PIP5K1A, PIP5K1C regulates phagocytosis by controlling distinct actin remodeling steps. It promotes particle attachment by generating PtdIns(4,5)P2 to induce controlled actin depolymerization, facilitating Fc-gamma-R clustering, and mediates RAC1-dependent actin filament reorganization. Additionally, it is involved in synaptic vesicle transport, plasma membrane PtdIns(4,5)P2 pool regulation (by similarity), clathrin- and AP-2-mediated endocytosis, cell junction assembly (by similarity), adherens junction formation (by similarity), focal adhesion dynamics, uropodium formation, and cell migration.
Gene ID
SwissProt ID
Synonyms
AI115456; AI835305; Pip5kIgamma
Molecular Weight

Predicted band size: 72 kDa; Observed band size: 90,87 kDa
Purity

Affinity Purified
Conjugation

Non-conjugated
Modification

Unmodified
Research Field

Signal Transduction
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Mouse
Dilution Ratio

WB: 1/500-1/1000;IP: 1/20
Application

WB, IP
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

Recombinant protein of mouse PIP5KI gamma
Database

Entrez Gene: 23396 Human ; 18717 Mouse ; 314641 Rat

SwissProt: O60331 Human ; O70161 Mouse ; Q5I6B8 Rat

OMIM: 611369 Human

Documentation
User Guide for Antibodies (1077 KB)

PIP5K1C Antibody (YA1644) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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PIP5K1C Antibody (YA1644)
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