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  4. Phospho-LAT (Tyr191) Antibody (YA1021)

Phospho-LAT (Tyr191) Antibody (YA1021)

Cat. No.: HY-P81297
COA User Guide for Antibodies Technical Support

Phospho-LAT (Tyr191) Antibody (YA1021) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-LAT (Tyr191).

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL In-stock
50 μL In-stock
100 μL In-stock
250 μL   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Phospho-LAT (Tyr191) Antibody (YA1021) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-LAT (Tyr191).

Background

The protein encoded by The related gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. The transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, The protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene ID
SwissProt ID
Synonyms
LAT; Linker for activation of T-cells family member 1; 36 kDa phospho-tyrosine adapter protein; pp36; p36-38
Molecular Weight

Predicted band size: 28 kDa; Observed band size: 38 kDa

Purity

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Phosphorylated

Research Field

Immunology

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

Dilution Ratio

WB: 1:500-1:1000; IHC: 1:50-1:100; IF: 1:50-1:200; IP: 1:30

Application

WB, IHC-P, ICC/IF, IP

Appearance

Liquid

Formulation

Supplied in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthesized peptide derived from human Phospho-LAT (Y191)

Database
Documentation

Phospho-LAT (Tyr191) Antibody (YA1021) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Phospho-LAT (Tyr191) Antibody (YA1021)
Cat. No.:
HY-P81297
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