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  5. Phospho-Jun/JunD (Ser73/Ser100) Antibody (YA2606)

Phospho-Jun/JunD (Ser73/Ser100) Antibody (YA2606)

Cat. No.: HY-P82861
User Guide for Antibodies Technical Support

Phospho-Jun/JunD (Ser73/Ser100) Antibody (YA2606) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2606), targeting Phospho-Jun/JunD (Ser73/Ser100), with a predicted molecular weight of 36 kDa (observed band size: 38,42,48 kDa). Phospho-Jun/JunD (Ser73/Ser100) Antibody (YA2606) can be used for WB, IP experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Phospho-Jun/JunD (Ser73/Ser100) Antibody (YA2606) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2606), targeting Phospho-Jun/JunD (Ser73/Ser100), with a predicted molecular weight of 36 kDa (observed band size: 38,42,48 kDa). Phospho-Jun/JunD (Ser73/Ser100) Antibody (YA2606) can be used for WB, IP experiment in human, mouse, rat background.
Background

c-Jun is a transcription factor that recognizes and binds to the AP-1 consensus motif 5'-TGA[GC]TCA-3'. It heterodimerizes with FOS family proteins to form the AP-1 transcription complex, enhancing both DNA binding and transcriptional activity (by similarity). Together with FOSB, it participates in activation-induced cell death of T cells by binding to the AP-1 promoter site of FASLG/CD95L and inducing its transcription upon TCR/CD3 signaling pathway activation. When phosphorylated by HIPK3, c-Jun promotes NR5A1 activity, boosting steroidogenic gene expression in response to cAMP pathway stimulation. In colorectal cancer (CRC) cells, it mediates KRAS-activated transcriptional upregulation of USP28 and directly binds to the USP28 promoter. During Epstein-Barr virus (EBV) infection, c-Jun binds to the viral BZLF1 Z promoter to activate BZLF1 expression.
Gene ID
SwissProt ID
Synonyms
JUN; Transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39; JUND; Transcription factor jun-D
Molecular Weight

Predicted band size: 36 kDa; Observed band size: 38,42,48 kDa
Purity

Affinity Purified
Conjugation

Non-conjugated
Modification

Phosphorylated
Research Field

Epigenetics and Nuclear Signaling
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Mouse, Rat
Dilution Ratio

WB: 1/500-1/1000;IP: 1/20
Application

WB, IP
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser73 of human Jun
Database

Entrez Gene: 3725 Human ; 3727 Human

SwissProt: P05412 Human ; P17535 Human

OMIM: 165160 Human ; 165162 Human

Documentation
User Guide for Antibodies (1077 KB)

Phospho-Jun/JunD (Ser73/Ser100) Antibody (YA2606) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Phospho-Jun/JunD (Ser73/Ser100) Antibody (YA2606)
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