Progesterone Receptor Antibody (YA3669)

Progesterone Receptor Antibody (YA3669) is a mouse-derived and non-conjugated IgG1 antibody, targeting to PGR. It can be applicated for WB, IHC-P, FC, ELISA assays, in the background of human, mouse.

The PR protein, as the B regulatory subunit of PP2A, is implicated in modulating substrate selectivity, catalytic activity, and directing the localization of the catalytic enzyme to specific subcellular compartments. PP2A, a phosphatase complex, consists of a core enzyme with a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A). This core dimer associates with various regulatory subunits, including the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59, R5/B'/B56 families, the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. The interplay between the PR protein and other regulatory subunits underscores its multifaceted role in shaping the substrate specificity, catalytic function, and subcellular localization of the PP2A enzyme, contributing to its diverse cellular functions.

P06401

Predicted band size: 99 kDa; Observed band size: 99/135 kDa

affinity purified.

Non-conjugated

Primary Antibody; Mouse Monoclonal Antibody

Mouse

Human, Mouse

WB: 1/500-1/2000; IHC: 1/200-1/1000; FC: 1/200-1/400; ELISA: 1/10000

WB, IHC-P, FC, ELISA

Liquid

Supplied in PBS with 0.05% sodium azide

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Purified recombinant fragment of human PGR (AA: 166-411) expressed in E. Coli.