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  5. PEX19 Antibody (YA2888)

PEX19 Antibody (YA2888)

Cat. No.: HY-P83143
User Guide for Antibodies Technical Support

PEX19 Antibody (YA2888) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2888), targeting PEX19, with a predicted molecular weight of 33 kDa (observed band size: 35,40 kDa). PEX19 Antibody (YA2888) can be used for WB, ICC/IF, IP, FC experiment in human, rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

PEX19 Antibody (YA2888) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2888), targeting PEX19, with a predicted molecular weight of 33 kDa (observed band size: 35,40 kDa). PEX19 Antibody (YA2888) can be used for WB, ICC/IF, IP, FC experiment in human, rat background.
Background

PEX19 protein plays a crucial role in early peroxisomal biogenesis, serving both as a cytosolic chaperone and an import receptor for peroxisomal membrane proteins (PMPs). Its function involves binding to and stabilizing newly synthesized PMPs in the cytoplasm, particularly through interactions with their hydrophobic membrane-spanning domains. Subsequently, PEX19 targets these PMPs to the peroxisome membrane by associating with the integral membrane protein PEX3. Notably, PEX19 engages in diverse protein-protein interactions, forming complexes with a spectrum of peroxisomal membrane proteins, such as PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14, and PEX16, as well as other crucial components like PXMP2/PMP22, PXMP4/PMP24, SLC25A17/PMP34, ABCD1/ALDP, ABCD2/ALDRP, and ABCD3/PMP70. Additionally, PEX19 plays a role in nuclear exclusion of CDKN2A, preventing its interaction with MDM2 and consequently facilitating the degradation of TP53. Furthermore, it interacts with the tumor suppressor CDKN2A/p19ARF, highlighting its involvement in intricate cellular processes.
Gene ID
SwissProt ID
Synonyms
HK33; PBD12A; Peroxin 19; PEX19; PMP1; PMPI; PXF; PXMP1
Molecular Weight

Predicted band size: 33 kDa; Observed band size: 35,40 kDa
Purity

Affinity Purified
Conjugation

Non-conjugated
Modification

Unmodified
Research Field

Tags & Cell Markers
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Rat
Dilution Ratio

WB: 1/500-1/1000;IF: 1/50-1/200;IP: 1/50;FC: 1/50-1/100
Application

WB, ICC/IF, IP, FC
Appearance

Liquid
Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

A synthesized peptide derived from human PEX19
Database

Entrez Gene: 5824 Human ;

SwissProt: P40855 Human ; Q9QYU1 Rat

OMIM: 614886 Human

Documentation
User Guide for Antibodies (1077 KB)

PEX19 Antibody (YA2888) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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