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  4. PCGF6 Antibody (YA1545)

PCGF6 Antibody (YA1545)

Cat. No.: HY-P81800
User Guide for Antibodies Technical Support

PCGF6 Antibody (YA1545) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1545), targeting PCGF6, with a predicted molecular weight of 40 kDa (observed band size: 40 kDa). PCGF6 Antibody (YA1545) can be used for WB, ICC/IF, IP experiment in mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

PCGF6 Antibody (YA1545) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1545), targeting PCGF6, with a predicted molecular weight of 40 kDa (observed band size: 40 kDa). PCGF6 Antibody (YA1545) can be used for WB, ICC/IF, IP experiment in mouse, rat background.

Background

PCGF6 is a transcriptional repressor that may modulate histone H3K4Me3 levels by activating the KDM5D histone demethylase. It is a component of the Polycomb group (PcG) multiprotein PRC1-like complex, a class of complexes required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. The PcG PRC1 complex acts through chromatin remodeling and histone modification, mediating monoubiquitination of histone H2A 'Lys-119', thereby heritably altering chromatin expressibility. Within the PRC1-like complex, PCGF6 regulates the ubiquitin ligase activity of RNF2.

Gene ID
SwissProt ID
Synonyms
RING finger protein 134; Mel18 and Bmi1-like RING finger
Molecular Weight

Predicted band size: 40 kDa; Observed band size: 40 kDa

Purity

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Epigenetics and Nuclear Signaling

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Mouse, Rat

Dilution Ratio

WB: 1/500-1/1000;IF: 1/50-1/200;IP: 1/20

Application

WB, ICC/IF, IP

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

Recombinant protein of mouse PCGF6

Database
Documentation

PCGF6 Antibody (YA1545) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PCGF6 Antibody (YA1545)
Cat. No.:
HY-P81800
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