NADPH Oxidase 4 Antibody (YA4513)

Cat. No.: HY-P84816: Data Sheet User Guide for Antibodies
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NADPH Oxidase 4 Antibody (YA4513) is a mouse-derived and non-conjugated IgG1 antibody, targeting to NOX4. It can be applicated for IHC-P, ICC/IF, FC, ELISA assays, in the background of human.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
Technical Parameters
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Documentation

Description	NADPH Oxidase 4 Antibody (YA4513) is a mouse-derived and non-conjugated IgG1 antibody, targeting to NOX4. It can be applicated for IHC-P, ICC/IF, FC, ELISA assays, in the background of human.
Background	NOX4 protein, a constitutive NADPH oxidase, functions as an intracellular superoxide generator upon complex formation with CYBA/p22phox. This enzyme plays a pivotal role in regulating signaling cascades, potentially through the inhibition of phosphatases. Additionally, NOX4 may act as an oxygen sensor, modulating the KCNK3/TASK-1 potassium channel and HIF1A activity. It is implicated in the regulation of insulin signaling cascades and may contribute to apoptosis, bone resorption, and lipolysaccharide-mediated activation of NFKB. Activated by insulin and inhibited by diphenylene iodonium, NOX4 is also responsive to plumbagin and can be activated by phorbol 12-myristate 13-acetate (PMA). These diverse regulatory functions highlight the versatile role of NOX4 in cellular processes and signaling pathways.
Gene ID	50507 [NCBI]
SwissProt ID	Q9NPH5
Synonyms	KOX; KOX-1; RENOX
Molecular Weight	Predicted band size: 67 kDa; Observed band size: 67 kDa
Purity	affinity purified.
Conjugation	Non-conjugated
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Host	Mouse
Reactivity	Human
Dilution Ratio	IHC: 1/200-1/1000; IF: 1/200-1/1000; FC: 1/200-1/400; ELISA: 1/10000
Application	IHC-P, ICC/IF, FC, ELISA
Appearance	Liquid
Formulation	Supplied in PBS with 0.05% sodium azide
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG1
Immunogen	Purified recombinant fragment of human NOX4 (AA: 210-310) expressed in E. Coli.
Documentation	Data Sheet (234 KB) User Guide for Antibodies (1077 KB)

NADPH Oxidase 4 Antibody (YA4513) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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NADPH Oxidase 4 Antibody (YA4513)

Biological Activity

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NADPH Oxidase 4 Antibody (YA4513) Related Classifications

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