MYST1 Antibody (YA4500)

MYST1 Antibody (YA4500) is a mouse-derived and non-conjugated IgG2b antibody, targeting to MYST1. It can be applicated for WB, IHC-P, ICC/IF, ELISA assays, in the background of human.

MYST1 Protein, identified as a histone acetyltransferase, is implicated in transcriptional activation, suggesting its potential role in modulating gene expression. Beyond its involvement in transcriptional processes, MYST1 may exert influence over the function of ATM. As a component of the MSL complex, MYST1 plays a critical role in acetylating nucleosomal histone H4, specifically generating H4K16ac, a modification associated with chromatin remodeling. Additionally, as part of the NSL complex, MYST1 may contribute to the acetylation of nucleosomal histone H4 on various lysine residues, although with less specificity compared to the MSL complex. Notably, MYST1 exhibits the capacity to acetylate TP53/p53 at 'Lys-120,' further broadening its functional repertoire in cellular processes beyond chromatin modification.

Q9H7Z6

Predicted band size: 52 kDa; Observed band size: 52 kDa

affinity purified.

Non-conjugated

Primary Antibody; Mouse Monoclonal Antibody

Mouse

Human

WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; ELISA: 1/10000

WB, IHC-P, ICC/IF, ELISA

Liquid

Supplied in PBS with 0.05% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG2b

Purified recombinant fragment of human MYST1 expressed in E. Coli.