MEF2A/MEF2C Antibody (YA3324)

Cat. No.: HY-P83579: Data Sheet User Guide for Antibodies
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MEF2A/MEF2C Antibody (YA3324) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3324), targeting MEF2A/MEF2C, with a predicted molecular weight of 51 kDa (observed band size: 51 kDa). MEF2A/MEF2C Antibody (YA3324) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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MEF2A/MEF2C Antibody (YA3324) Featured Recommendations:

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

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Description	MEF2A/MEF2C Antibody (YA3324) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3324), targeting MEF2A/MEF2C, with a predicted molecular weight of 51 kDa (observed band size: 51 kDa). MEF2A/MEF2C Antibody (YA3324) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.
Background	MEF2C is a transcription activator that specifically binds to the MEF2 element found in the regulatory regions of many muscle-specific genes. It controls cardiac morphogenesis and myogenesis and is involved in vascular development. MEF2C enhances transcriptional activation mediated by SOX18 and plays a vital role in hippocampal-dependent learning and memory by suppressing excitatory synapse numbers, thereby regulating basal and evoked synaptic transmission. It is crucial for normal neuronal development, distribution, and electrical activity in the neocortex and is necessary for the proper development of megakaryocytes, platelets, and bone marrow B-lymphopoiesis. MEF2C is also required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens, and normal induction of germinal center B-cells. By similarity, it may also contribute to neurogenesis and cortical architecture development. Isoforms lacking the repressor domain exhibit higher activity than isoform 1.
Gene ID	4205 [NCBI]
SwissProt ID	Q06413 / Q02078
Synonyms	ADCAD1; MEF2; MEF2A; Myocyte enhancer factor 2A; RSRFC4; RSRFC9
Molecular Weight	Predicted band size: 51 kDa; Observed band size: 51 kDa
Purity	Affinity Chromatography
Conjugation	Non-conjugated
Modification	Unmodified
Research Field	Signal Transduction
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Recombinant, Monoclonal
Host	Rabbit
Reactivity	Human, Mouse, Rat
Dilution Ratio	WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;FC: 1/50-1/100
Application	WB, IHC-P, ICC/IF, FC
Appearance	Liquid
Formulation	Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Sensitivity	Endogenous
Immunogen	A synthesized peptide derived from human MEF2A+MEF2C
Database	Entrez Gene: 4205 Human ; 4208 Human ; 17258 Mouse ; 17260 Mouse ; 309957 Rat 499497 SwissProt: Q02078 Human ; Q06413 Human ; Q60929 Mouse ; Q8CFN5 Mouse ; Q2MJT0 Rat OMIM: 608320 Human
Documentation	Data Sheet (235 KB) User Guide for Antibodies (1077 KB)

MEF2A/MEF2C Antibody (YA3324) Related Classifications

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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MEF2A/MEF2C Antibody (YA3324)

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