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  5. MCM4 Antibody (YA2708)

MCM4 Antibody (YA2708)

Cat. No.: HY-P82963
User Guide for Antibodies Technical Support

MCM4 Antibody (YA2708) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MCM4.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.
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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

MCM4 Antibody (YA2708) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MCM4.
Background

MCM4 is a core component of the MCM2-7 complex, which serves as the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. It forms part of the CDC45-MCM-GINS (CMG) helicase, the molecular machine responsible for unwinding template DNA during replication and serving as the foundation for replisome assembly. The active ATPase sites within the MCM2-7 ring are generated through interfaces between neighboring subunits, where a conserved arginine finger motif is provided in trans relative to the Walker A box ATP-binding site of the adjacent subunit. Notably, the six ATPase active sites likely contribute unevenly to the overall helicase activity. by similar: This functional description also applies to other MCM2-7 complex members.
Gene ID
SwissProt ID
Synonyms
MCM4; CDC21; DNA replication licensing factor MCM4; CDC21 homolog; P1-CDC21
Molecular Weight

Predicted band size: 97 kDa; Observed band size: 97 kDa
Purity

Affinity Purified
Conjugation

Non-conjugated
Modification

Unmodified
Research Field

Epigenetics and Nuclear Signaling
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Mouse
Dilution Ratio

WB: 1:500-1:1000; IP: 1:50; FC: 1:50-1:100
Application

WB, IP, FC
Appearance

Liquid
Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

A synthesized peptide derived from human MCM4
Database

Entrez Gene: 4173 Human ; 17217 Mouse ;

SwissProt: P33991 Human ; P49717 Mouse ;

OMIM: 609981 Human

Documentation
User Guide for Antibodies (1077 KB)

MCM4 Antibody (YA2708) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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MCM4 Antibody (YA2708)
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