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  5. MCM4 Antibody (YA2708)

MCM4 Antibody (YA2708)

Cat. No.: HY-P82963
User Guide for Antibodies Technical Support

MCM4 Antibody (YA2708) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2708), targeting MCM4, with a predicted molecular weight of 97 kDa (observed band size: 97 kDa). MCM4 Antibody (YA2708) can be used for WB, IP, FC experiment in human, mouse background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

MCM4 Antibody (YA2708) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2708), targeting MCM4, with a predicted molecular weight of 97 kDa (observed band size: 97 kDa). MCM4 Antibody (YA2708) can be used for WB, IP, FC experiment in human, mouse background.
Background

MCM4 is a core component of the MCM2-7 complex, which serves as the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. It forms part of the CDC45-MCM-GINS (CMG) helicase, the molecular machine responsible for unwinding template DNA during replication and serving as the foundation for replisome assembly. The active ATPase sites within the MCM2-7 ring are generated through interfaces between neighboring subunits, where a conserved arginine finger motif is provided in trans relative to the Walker A box ATP-binding site of the adjacent subunit. Notably, the six ATPase active sites likely contribute unevenly to the overall helicase activity. by similar: This functional description also applies to other MCM2-7 complex members.
Gene ID
SwissProt ID
Synonyms
MCM4; CDC21; DNA replication licensing factor MCM4; CDC21 homolog; P1-CDC21
Molecular Weight

Predicted band size: 97 kDa; Observed band size: 97 kDa
Purity

Affinity Purified
Conjugation

Non-conjugated
Modification

Unmodified
Research Field

Epigenetics and Nuclear Signaling
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Mouse
Dilution Ratio

WB: 1/500-1/1000;IP: 1/50;FC: 1/50-1/100
Application

WB, IP, FC
Appearance

Liquid
Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

A synthesized peptide derived from human MCM4
Database

Entrez Gene: 4173 Human ; 17217 Mouse ;

SwissProt: P33991 Human ; P49717 Mouse ;

OMIM: 609981 Human

Documentation
User Guide for Antibodies (1077 KB)

MCM4 Antibody (YA2708) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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MCM4 Antibody (YA2708)
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