Matrilin-1 Antibody (YA4960)

Matrilin-1 Antibody (YA4960) is a mouse-derived and non-conjugated monoclonal antibody, targeting to Matrilin-1. It can be applicated for WB, ICC/IF, ELISA assays, in the background of human.

MATN1 is a major component of the extracellular matrix of non-articular cartilage (By similarity). It binds to type 2 collagens and forms long concatenated protein networks as part of the extracellular matrix (By similarity). MATN1 is required for the network-like organization and bundling of collagen fibrils surrounding chondrocytes in the zones of maturation and hypertrophy (By similarity). It plays a role in mechanotransduction and adaptation to mechanical loading in cartilage chondrocytes, leading to increased expression of extracellular matrix components ACAN and COL2A1 (By similarity). Additionally, MATN1 acts as a moderator of angiogenesis in response to injury (By similarity).

P21941

Predicted band size: 54 kDa;

affinity purified.

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human

WB: 1:500-1:2000; ICC/IF: 1:200-1:1000; ELISA: 1:10000

WB, ICC/IF, ELISA

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

Purified recombinant fragment of human Matrilin-1 expressed in E. Coli.