Lamin B1 Antibody (YA3871)

Lamin B1 Antibody (YA3871) is a mouse-derived and non-conjugated IgG1 antibody, targeting to LMNB1. It can be applicated for WB, IHC-P, ICC/IF, FC, ELISA assays, in the background of human, mouse, rat.

Lamin B1 is an intermediate filament protein that assembles into a filamentous meshwork and constitutes a major component of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane. Lamins provide a structural framework for the nuclear envelope, bridging it with chromatin, and play a crucial role in nuclear assembly, chromatin organization, nuclear membrane dynamics, and telomere regulation. The structural integrity of the lamina is tightly controlled by the cell cycle, as evidenced by the disassembly and reassembly of the nuclear envelope during prophase and telophase, respectively. by similar: Lamins are key members of the intermediate filament protein family, essential for maintaining nuclear structure and function.

P20700 

Predicted band size: 66 kDa; Observed band size: 66 kDa

affinity purified.

Non-conjugated

Primary Antibody; Mouse Monoclonal Antibody

Mouse

Human, Mouse, Rat

WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FC: 1/200-1/400; ELISA: 1/10000

WB, IHC-P, ICC/IF, FC, ELISA

Liquid

Supplied in PBS with 0.05% sodium azide

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Purified recombinant fragment of human LMNB1 (AA: 413-583) expressed in HEK293-6e cells supernatant.