LCAT Antibody (YA2864)

Cat. No.: HY-P83119: Data Sheet User Guide for Antibodies
FAQs
Technical Support

LCAT Antibody (YA2864) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2864), targeting LCAT, with a predicted molecular weight of 50 kDa (observed band size: 55 kDa). LCAT Antibody (YA2864) can be used for WB, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

Synthetic products have potential research and development risk.

or Bulk Inquiry

* Please select Quantity before adding items.

LCAT Antibody (YA2864) Featured Recommendations:

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
Technical Parameters
Properties
Documentation

Description	LCAT Antibody (YA2864) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2864), targeting LCAT, with a predicted molecular weight of 50 kDa (observed band size: 55 kDa). LCAT Antibody (YA2864) can be used for WB, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.
Background	LCAT, a pivotal enzyme in the extracellular metabolism of plasma lipoproteins, is primarily synthesized in the liver and secreted into the plasma. In this crucial role, LCAT converts cholesterol and phosphatidylcholines (lecithins) on the surface of both high and low-density lipoproteins (HDLs and LDLs) to cholesteryl esters and lysophosphatidylcholines. The resulting cholesteryl esters are transported back to the liver. LCAT exhibits a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines. Beyond its hepatic functions, LCAT is produced in the brain by primary astrocytes, where it esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia, influencing cerebral spinal fluid (CSF) APOE- and APOA1 levels. In collaboration with APOE and the cholesterol transporter ABCA1, LCAT plays a pivotal role in the maturation of glial-derived, nascent lipoproteins. Additionally, LCAT is essential for remodeling high-density lipoprotein particles into their spherical forms and catalyzes the hydrolysis of platelet-activating factor (PAF) to lyso-PAF, as well as the esterification of (24S)-hydroxycholesterol (24(S)OH-C), known as cerebrosterol, to produce 24(S)OH-C monoesters.
Gene ID	3931 [NCBI]
SwissProt ID	P04180
Synonyms	LCAT
Molecular Weight	Predicted band size: 50 kDa; Observed band size: 55 kDa
Purity	Affinity Purified
Conjugation	Non-conjugated
Modification	Unmodified
Research Field	Cardiovascular
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Recombinant, Monoclonal
Host	Rabbit
Reactivity	Human, Mouse, Rat
Dilution Ratio	WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/50
Application	WB, IHC-P, ICC/IF, IP
Appearance	Liquid
Formulation	Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Sensitivity	Endogenous
Immunogen	A synthesized peptide derived from human LCAT
Database	Entrez Gene: 3931 Human ; 16816 Mouse ; 24530 Rat SwissProt: P04180 Human ; P16301 Mouse ; P18424 Rat OMIM: 245900 Human
Documentation	Data Sheet (235 KB) User Guide for Antibodies (1077 KB)

LCAT Antibody (YA2864) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Product Name

Requested Quantity *

Applicant Name *

Salutation

Email Address *

Phone Number *

Department

Organization Name *

City

State

Country or Region *

Remarks

Product Name

Lot #

Applicant Name *

Country or Region *

Email Address *

Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

LCAT Antibody (YA2864)

LCAT Antibody (YA2864) Featured Recommendations:

Biological Activity

Technical Parameters

Properties

Documentation

LCAT Antibody (YA2864) Related Classifications

Your Recently Viewed Products:

Request for HNMR Report

SAFETY DATA SHEET (SDS)

Request for HNMR Report