KMT2C Antibody (YA4374)

KMT2C Antibody (YA4374) is a mouse-derived and non-conjugated IgG1 antibody, targeting to KMT2C. It can be applicated for IHC-P, ICC/IF, FC, ELISA assays, in the background of human.

KMT2C is a histone methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of Lys-4 on histone H3 (H3K4). As part of the chromatin remodeling machinery, it predominantly generates H3K4me1 methylation marks at active chromatin sites where transcription and DNA repair occur. Similar to KMT2D (by similar), KMT2C likely plays a redundant role in enriching the H3K4me1 mark on primed and active enhancer elements.

Q8NEZ4

Predicted band size: 541 kDa; Observed band size: 269 kDa

affinity purified.

Non-conjugated

Primary Antibody; Mouse Monoclonal Antibody

Mouse

Human

IHC: 1/200-1/1000; IF: 1/200-1/1000; FC: 1/200-1/400; ELISA: 1/10000

IHC-P, ICC/IF, FC, ELISA

Liquid

Supplied in PBS with 0.05% sodium azide

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Purified recombinant fragment of human KMT2C (AA: 1-205) expressed in E. Coli.