2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. KDM5C/Jarid1C/SMCX Antibody (YA5174)

KDM5C/Jarid1C/SMCX Antibody (YA5174)

Cat. No.: HY-P85482
User Guide for Antibodies Technical Support

KDM5C/Jarid1C/SMCX Antibody (YA5174) is a mouse-derived and non-conjugated monoclonal antibody, targeting to KDM5C/Jarid1C/SMCX. It can be applicated for WB, ICC assays, in the background of human.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

KDM5C/Jarid1C/SMCX Antibody (YA5174) is a mouse-derived and non-conjugated monoclonal antibody, targeting to KDM5C/Jarid1C/SMCX. It can be applicated for WB, ICC assays, in the background of human.
Background

KDM5C/Jarid1C/SMCX is a histone demethylase that specifically targets 'Lys-4' of histone H3, playing a central role in histone code regulation. It does not act on 'Lys-9', 'Lys-27', 'Lys-36', or 'Lys-79' of H3, nor 'Lys-20' of H4, and only demethylates trimethylated and dimethylated (but not monomethylated) H3 'Lys-4'. It participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST to neuron-restrictive silencer elements. Additionally, it represses CLOCK-BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).
Gene ID
SwissProt ID
Synonyms
DXS1272E; Histone demethylase JARID1C; JARID1C; JmjC domain containing protein SMCX; Jumonji AT rich interactive domain 1C; Jumonji, AT rich interactive domain 1C; RBP2 like; Jumonji/ARID domain-containing protein 1C; KDM5C; KDM5C_HUMAN; Lysine; K; specific demethylase 5C; Lysine-specific demethylase 5C; MRXJ; MRXSCJ; MRXSJ; Protein SmcX; Protein Xe169; rbp2 like protein; Selected cDNA on X; SMCX; Smcx homolog X chromosome; SmcX protein; SmcX protein; Smcy homolog X linked; XE169; Xe169 protein; Xe169 protein.
Molecular Weight

Observed band size: 220 kDa
Purity

affinity chromatography.
Conjugation

Non-conjugated
Modification

Unmodified
Product Categories

Primary Antibody; Mouse Monoclonal Antibody
Clonality

Monoclonal
Host

Mouse
Reactivity

Human
Dilution Ratio

WB: 1:1000; ICC: 1:150
Application

WB, ICC
Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Immunogen

Purified recombinant human KDM5C / Jarid1C / SMCX protein fragments expressed in E.coli
Documentation
User Guide for Antibodies (1077 KB)

KDM5C/Jarid1C/SMCX Antibody (YA5174) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
KDM5C/Jarid1C/SMCX Antibody (YA5174)
Cat. No.:
HY-P85482
Quantity:
MCE Japan Authorized Agent:

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Country or Region *

Email Address *

     

Phone Number *

 

Organization Name *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.