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  2. Primary Antibodies
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  4. HPS-1 Antibody (YA4895)

HPS-1 Antibody (YA4895)

Cat. No.: HY-P85203
User Guide for Antibodies Technical Support

HPS-1 Antibody (YA4895) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to HPS-1.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

HPS-1 Antibody (YA4895) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to HPS-1.

Background

HPS-1 is a component of the BLOC-3 complex, which functions as a guanine exchange factor (GEF) for RAB32 and RAB38, facilitating the exchange of GDP to GTP and converting them from an inactive GDP-bound state to an active GTP-bound state. The BLOC-3 complex plays a key role in regulating melanin production and melanosome biogenesis, and it promotes the membrane localization of RAB32 and RAB38.

Gene ID
SwissProt ID
Synonyms
HPS1; HPS; Hermansky-Pudlak syndrome 1 protein
Molecular Weight

Predicted band size: 79 kDa;

Purity

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Product Categories

Primary Antibody; Mouse Monoclonal Antibody

Clonality

Monoclonal

Host

Mouse

Reactivity

Human

Dilution Ratio

WB: 1:500-1:2000; ELISA: 1:10000

Application

WB, ELISA

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Immunogen

Purified recombinant fragment of HPS-1 expressed in E. Coli.

Documentation

HPS-1 Antibody (YA4895) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
HPS-1 Antibody (YA4895)
Cat. No.:
HY-P85203
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