HP1 alpha Antibody (YA6175)

HP1 alpha Antibody (YA6175) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HP1α. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

CBX5 is a component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. However, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). CBX5 may contribute to the association of heterochromatin with the inner nuclear membrane through interactions with the lamin-B receptor (LBR). Additionally, it is involved in the formation of kinetochores via interaction with the MIS12 complex subunit NSL1 and is required for the formation of the inner centromere.

P45973

Predicted band size: 22 kDa; Observed band size: 22 kDa

Protein A

Non-conjugated

Unmodified

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Monoclonal

Rabbit

Human, Mouse, Rat

IHC: 1:400-1:2000; WB: 1:1000-1:5000; ICC/IF: 1:200-1:1000; ELISA: 1:5000-1:20000; IP: 1:50-1:200,

WB, IHC-P, ICC/IF, IP, ELISA

Liquid

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG