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  4. HNF4α Antibody (YA5852)

HNF4α Antibody (YA5852)

Cat. No.: HY-P86160
User Guide for Antibodies Technical Support

HNF4α Antibody (YA5852) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HNF4α. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

HNF4α Antibody (YA5852) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HNF4α. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

Background

HNF4A is a transcriptional regulator that controls hepatic gene expression during the transition of endodermal cells to hepatic progenitor cells, facilitating RNA pol II recruitment to target gene promoters. It activates the transcription of CYP2C38 (By similarity). Additionally, HNF4A represses CLOCK-BMAL1 transcriptional activity and is essential for circadian rhythm maintenance and period regulation in liver and colon cells (PubMed:30530698).

Gene ID
SwissProt ID
Synonyms
HNF4A; HNF4; NR2A1; TCF14; Hepatocyte nuclear factor 4-alpha; HNF-4-alpha; Nuclear receptor subfamily 2 group A member 1; Transcription factor 14; TCF-14; Transcription factor HNF-4
Molecular Weight

Predicted band size: 53 kDa; Observed band size: 53 kDa

Purity

Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

Dilution Ratio

IHC: 1:1000-1:5000; WB: 1:2000-1:10000; ICC/IF: 1:200-1:1000; ELISA: 1:5000-1:20000; IP: 1:50-1:200;

Application

WB, IHC-P, ICC/IF, IP, ELISA

Appearance

Liquid

Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Documentation

HNF4α Antibody (YA5852) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
HNF4α Antibody (YA5852)
Cat. No.:
HY-P86160
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