Histone H2B (acetyl K20) Antibody (YA377)

Cat. No.: HY-P80164: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

Histone H2B (acetyl K20) Antibody (YA377) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H2B (acetyl K20).

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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Histone H2B (acetyl K20) Antibody (YA377) Featured Recommendations:

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

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Description	Histone H2B (acetyl K20) Antibody (YA377) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H2B (acetyl K20).
Background	Histone H2B is a core component of nucleosomes, which wrap and compact DNA into chromatin, thereby limiting DNA accessibility to cellular machineries that require DNA as a template. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. DNA accessibility is regulated through a complex set of post-translational modifications of histones, known as the histone code, and nucleosome remodeling. Additionally, Histone H2B exhibits broad antibacterial activity and may contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, as well as the bactericidal activity of amniotic fluid.
Tag	Free
Gene ID	337874 [NCBI]
SwissProt ID	O60814
Molecular Weight	Predicted band size: 14 kDa; Observed band size: 14 kDa
Purity	Protein A affinity purified.
Subcellular Location	Chromosome, Nucleosome core, Nucleus.
Conjugation	Non-conjugated
Modification	Acetylated
Research Field	Epigenetics and Nuclear Signaling
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Recombinant, Monoclonal
Host	Rabbit
Reactivity	Human, Mouse
Dilution Ratio	WB: 1:1,000 ;ICC/IF: 1:100-1:500 ;IHC-P: 1:100-1:500 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.
Application	WB, ICC/IF, IHC-P, FC, IP, ChIP
Appearance	Liquid
Formulation	Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Sensitivity	Endogenous
Immunogen	Synthetic peptide corresponding to Human Histone H2B.AA range:1-49.
Database	Entrez Gene: 337874 Human ; 54145 Human ; 8349 Human ; 104021 Mouse ; SwissProt: O60814 Human ; P06899 Human ; P23527 Human ; P33778 Human ; P57053 Human ; P58876 Human ; P62807 Human ; Q16778 Human ; Q5QNW6 Human ; Q8N257 Human ; Q93079 Human ; Q99877 Human ; Q99879 Human ; Q99880 Human ; P10854 Mouse ; Q64475 Mouse ; OMIM: 615045 Human
Documentation	Select Batch: Data Sheet (234 KB) SDS (251 KB) COA (206 KB) User Guide for Antibodies (1077 KB)

Histone H2B (acetyl K20) Antibody (YA377) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Histone H2B (acetyl K20) Antibody (YA377)

Histone H2B (acetyl K20) Antibody (YA377) Featured Recommendations:

Biological Activity

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Histone H2B (acetyl K20) Antibody (YA377) Related Classifications

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