Galectin-3 Antibody (YA5715)

Galectin-3 Antibody (YA5715) is a mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Galectin-3. It can be applicated for IHC-P, ELISA assays, in the background of human.

Galectin-3 is a galactose-specific lectin that binds IgE. It may mediate CSPG4-stimulated endothelial cell migration through interaction with alpha-3, beta-1 integrin. By similarity, Galectin-3 cooperates with DMBT1 to regulate terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus, it functions as a pre-mRNA splicing factor. It is involved in acute inflammatory responses, including neutrophil activation/adhesion, monocyte/macrophage chemotaxis, opsonization of apoptotic neutrophils, and mast cell activation. Together with TRIM16, it coordinates membrane damage recognition by mobilizing core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.

P17931

Predicted band size: 26 kDa; Observed band size: 33 kDa

affinity chromatography.

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human

IHC: 1:50-100; ELISA: 1:500-5000

IHC-P, ELISA

Liquid

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG2b

Synthesized peptide derived from human Galectin 3 AA range: 150-250