FBXL10 Antibody (YA4378)

Cat. No.: HY-P84681: Data Sheet User Guide for Antibodies
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FBXL10 Antibody (YA4378) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to FBXL10.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
Technical Parameters
Properties
Documentation

Description	FBXL10 Antibody (YA4378) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to FBXL10.
Background	FBXL10 is a histone demethylase that specifically removes methylation modifications at 'Lys-4' and 'Lys-36' sites of histone H3, playing a central role in histone code regulation. This enzyme preferentially targets trimethylated H3 'Lys-4' and dimethylated H3 'Lys-36' residues but exhibits weak or no activity toward mono- or trimethylated H3 'Lys-36'. FBXL10 primarily binds to the transcribed region of ribosomal RNA and represses ribosomal RNA gene transcription, thereby inhibiting cell growth and proliferation. Additionally, it may function as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Gene ID	84678 [NCBI]
SwissProt ID	Q8NHM5
Synonyms	CXXC2; Fbl10; PCCX2; KDM2B; JHDM1B
Molecular Weight	Predicted band size: 153 kDa; Observed band size: 153 kDa
Purity	affinity purified.
Conjugation	Non-conjugated
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Clonality	Monoclonal Antibody
Host	Mouse
Reactivity	Human
Dilution Ratio	WB: 1:500-1:2000; FC: 1:200-1:400; ELISA: 1:10000
Application	WB, FC, ELISA
Appearance	Liquid
Formulation	Supplied in PBS with 0.05% sodium azide
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG2b
Immunogen	Purified recombinant fragment of human FBXL10 (AA: 457-555) expressed in E. Coli.
Documentation	Data Sheet (234 KB) User Guide for Antibodies (1077 KB)

FBXL10 Antibody (YA4378) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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FBXL10 Antibody (YA4378)

Biological Activity

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FBXL10 Antibody (YA4378) Related Classifications

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