Fascin Antibody (YA445)

Cat. No.: HY-P80127: Data Sheet User Guide for Antibodies
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Fascin Antibody (YA445) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Fascin.

For research use only. We do not sell to patients.

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10 μL		Ask For Quote & Lead Time
50 μL		Ask For Quote & Lead Time
100 μL		Ask For Quote & Lead Time

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Fascin Antibody (YA445) Featured Recommendations:

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
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Description	Fascin Antibody (YA445) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Fascin.
Background	Fascin is an actin-binding protein that contains two major actin binding sites. It organizes filamentous actin into parallel bundles and plays a role in the arrangement of actin filament bundles, as well as the formation of microspikes, membrane ruffles, and stress fibers. Fascin is essential for the formation of various cell protrusions, such as filopodia, and for cell motility and migration. Additionally, it mediates the reorganization of the actin cytoskeleton and promotes axon growth cone collapse in response to NGF. By similar studies, Fascin has been shown to have broad functions in cytoskeletal dynamics regulation.
Tag	Free
Gene ID	6624 [NCBI]
SwissProt ID	Q16658
Molecular Weight	Predicted band size: 54 kDa; Observed band size: 54 kDa
Purity	Protein A affinity purified.
Subcellular Location	Cytoskeleton, stress fiber, cytosol, cell cortex, filopodium, invadopodium, microvillus, cell junction.
Conjugation	Non-conjugated
Modification	Unmodified
Research Field	Cell Biology
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Recombinant, Monoclonal
Host	Rabbit
Reactivity	Human, Mouse, Rat
Dilution Ratio	WB: 1:500-1:2000; ICC/IF: 1:50-1:200; IHC-P: 1:50-1:200; FC: 1:50-1:100; IP: Use at an assay dependent concentration.
Application	WB, ICC/IF, IHC-P, FC, IP
Appearance	Liquid
Formulation	Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Sensitivity	Endogenous
Immunogen	Synthetic peptide corresponding to Human Fascin.AA range:221-389.
Database	Entrez Gene: 6624 Human ; 14086 Mouse ; 683788 Rat SwissProt: Q16658 Human ; Q61553 Mouse ; P85845 Rat OMIM: 602689 Human
Documentation	Data Sheet (234 KB) User Guide for Antibodies (1077 KB)

Fascin Antibody (YA445) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Fascin Antibody (YA445)

Fascin Antibody (YA445) Featured Recommendations:

Biological Activity

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Fascin Antibody (YA445) Related Classifications

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