ERG Antibody (YA5547)

ERG Antibody (YA5547) is a mouse-derived and non-conjugated IgG3 monoclonal antibody, targeting to ERG. It can be applicated for WB, ICC/IF, ELISA assays, in the background of human.

ERG, a transcriptional regulator, is implicated in the modulation of gene expression by potentially facilitating transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure. Moreover, ERG has been identified as part of an IGF2BP1-dependent mRNP granule complex that contains untranslated mRNAs, suggesting its involvement in post-transcriptional processes. The interaction with SETDB1 underscores its role in the dynamic interplay of molecular components within cellular pathways, contributing to the intricate regulation of gene expression and chromatin organization.

P11308

Predicted band size: 55 kDa; Observed band size: 68 kDa

Protein G

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human

WB: 1:500-2000; ICC/IF: 1:100-500; ELISA: 1:1000-5000

WB, ICC/IF, ELISA

Liquid

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG3

Synthesized peptide derived from human ERG AA range: 200-300