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  5. EBI3 Antibody (YA2692)

EBI3 Antibody (YA2692)

Cat. No.: HY-P82947
User Guide for Antibodies Technical Support

EBI3 Antibody (YA2692) is a non-conjugated IgG antibody, targeting EBI3, with a predicted molecular weight of 25 kDa (observed band size: 25 kDa). EBI3 Antibody (YA2692) can be used for WB experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

EBI3 Antibody (YA2692) is a non-conjugated IgG antibody, targeting EBI3, with a predicted molecular weight of 25 kDa (observed band size: 25 kDa). EBI3 Antibody (YA2692) can be used for WB experiment in human, mouse, rat background.
Background

EBI3 associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine functioning in innate immunity. IL-27 exhibits both pro- and anti-inflammatory properties, regulating T-helper cell development, suppressing T-cell proliferation, stimulating cytotoxic T-cell activity, inducing isotype switching in B-cells, and exerting diverse effects on innate immune cells. Its target cells include CD4 T-helper cells, which can differentiate into type 1 effector cells (TH1), type 2 effector cells (TH2), and IL17-producing helper T-cells (TH17). It drives rapid clonal expansion of naive CD4 T-cells but not memory CD4 T-cells. IL-27 strongly synergizes with IL-12 to trigger interferon-gamma (IFN-gamma) production in naive CD4 T-cells and binds to the cytokine receptor WSX-1/TCCR. Additionally, IL-27 demonstrates antitumor and antiangiogenic activities by activating the production of antiangiogenic chemokines.
Gene ID
SwissProt ID
Synonyms
EBI3; IL27B; Interleukin-27 subunit beta; IL-27 subunit beta; IL-27B; Epstein-Barr virus-induced gene 3 protein; EBV-induced gene 3 protein
Molecular Weight

Predicted band size: 25 kDa; Observed band size: 25 kDa
Purity

Affinity Purified
Conjugation

Non-conjugated
Modification

Unmodified
Research Field

Immunology
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Mouse, Rat
Dilution Ratio

WB: 1/500-1/1000
Application

WB
Appearance

Liquid
Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

A synthesized peptide derived from human EBI3
Database

Entrez Gene: 10148 Human ; 50498 Mouse ; 680609 Rat

SwissProt: Q14213 Human ; O35228 Mouse ;

OMIM: 605816 Human

Documentation
User Guide for Antibodies (1077 KB)

EBI3 Antibody (YA2692) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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EBI3 Antibody (YA2692)
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