2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. DLX5 Antibody (YA2342)

DLX5 Antibody (YA2342) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2342), targeting DLX5, with a predicted molecular weight of 32 kDa (observed band size: 32 kDa). DLX5 Antibody (YA2342) can be used for WB, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

DLX5 Antibody (YA2342) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2342), targeting DLX5, with a predicted molecular weight of 32 kDa (observed band size: 32 kDa). DLX5 Antibody (YA2342) can be used for WB, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.
Background

DLX5 is a transcriptional factor involved in bone development, functioning as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. It stimulates ALPL promoter activity in a RUNX2-independent manner and enhances SP7 promoter activity during osteoblast differentiation. Additionally, DLX5 promotes cell proliferation by upregulating MYC promoter activity and acts as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. It binds to the homeodomain-response element of the ALPL and SP7 promoters, as well as the MYC promoter, requiring the 5'-TAATTA-3' consensus sequence for DNA binding.
Gene ID
SwissProt ID
Synonyms
Distal less homeo box 5; Dlx 5; Homeo box protein DLX 5
Molecular Weight

Predicted band size: 32 kDa; Observed band size: 32 kDa
Purity

Affinity Chromatography
Conjugation

Non-conjugated
Modification

Unmodified
RRID
Research Field

Neuroscience
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Mouse, Rat
Dilution Ratio

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/50
Application

WB, IHC-P, ICC/IF, IP
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

A synthesized peptide derived from human Dlx5
Database

Entrez Gene: 1749 Human ; 13395 Mouse ; 25431 Rat

SwissProt: P56178 Human ; P70396 Mouse ; P50575 Rat

OMIM: 220600 Human

Documentation
SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

DLX5 Antibody (YA2342) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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DLX5 Antibody (YA2342)
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HY-P82597
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