DDR2 Antibody (YA4319)

Cat. No.: HY-P84622: Data Sheet User Guide for Antibodies
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DDR2 Antibody (YA4319) is a mouse-derived and non-conjugated IgG2a antibody, targeting to DDR2. It can be applicated for IHC-P, ICC/IF, FC, ELISA assays, in the background of human, mouse, rat, rabbit.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
Technical Parameters
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Documentation

Description	DDR2 Antibody (YA4319) is a mouse-derived and non-conjugated IgG2a antibody, targeting to DDR2. It can be applicated for IHC-P, ICC/IF, FC, ELISA assays, in the background of human, mouse, rat, rabbit.
Background	DDR2 protein, a tyrosine kinase integral to the regulation of tissue remodeling, functions as a cell surface receptor for fibrillar collagen, exerting control over cell differentiation, extracellular matrix remodeling, cell migration, and proliferation. Crucial for normal bone development, DDR2 plays a central role in osteoblast differentiation and chondrocyte maturation through a signaling pathway involving MAP kinases, culminating in the activation of the transcription factor RUNX2. Additionally, DDR2 regulates extracellular matrix remodeling by up-regulating collagenases MMP1, MMP2, and MMP13, thereby facilitating cell migration and tumor cell invasion. Its involvement extends to promoting fibroblast migration and proliferation, contributing to the dynamic process of cutaneous wound healing.
Gene ID	4921 [NCBI]
SwissProt ID	Q16832
Synonyms	TKT; MIG20a; NTRKR3; TYRO10
Molecular Weight	Predicted band size: 97 kDa; Observed band size: 97 kDa
Purity	affinity purified.
Conjugation	Non-conjugated
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Host	Mouse
Reactivity	Human, Mouse, Rat, Rabbit
Dilution Ratio	IHC: 1/200-1/1000; IF: 1/200-1/1000; FC: 1/200-1/400; ELISA: 1/10000
Application	IHC-P, ICC/IF, FC, ELISA
Appearance	Liquid
Formulation	Supplied in PBS with 0.05% sodium azide.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG2a
Immunogen	Purified recombinant fragment of human DDR2 expressed in E. Coli.
Documentation	Data Sheet (234 KB) User Guide for Antibodies (1077 KB)

DDR2 Antibody (YA4319) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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DDR2 Antibody (YA4319)

Biological Activity

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DDR2 Antibody (YA4319) Related Classifications

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