Cytokeratin 15 Antibody (YA5724)

Cytokeratin 15 Antibody (YA5724) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Cytokeratin 15. It can be applicated for IHC-P, ELISA assays, in the background of human.

Cytokeratins (CK) are keratin proteins exclusively found in epithelial tissues, classified as type I (acidic) and type II (basic). As the largest subgroup of intermediate filaments, they form the eukaryotic cytoskeleton alongside other filaments, functioning in epithelial integrity maintenance, injury protection, and cellular communication. Expressed in pairs and numbered 1–20 by molecular weight/isoelectric point, they include simple epithelial types (e.g., CK7, CK8, CK18–20) and complex types (e.g., cutaneous CK5/6, CK10, CK14–15). An alternative system categorizes acidic type I (low MW, CK9–20) and basic type II (high MW, CK1–8). Monoclonal antibodies with varying specificity target these proteins. Released during epithelial stress, Cytokeratins are detectable via commercial UBC Rapid assays (ELISA/point-of-care), showing 59.3% sensitivity and 86.1% specificity, particularly for primary high-grade tumors. by similar: UBC Rapid is developed by IDL Biotech AB.

P19012

Predicted band size: 49 kDa; Observed band size: 49 kDa

affinity chromatography.

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human

IHC: 1:200-400; ELISA: 1:500-5000

IHC-P, ELISA

Liquid

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Synthesized peptide derived from human CK15 AA range: 350-456