Cytochrome C Antibody (YA5422)

Cytochrome C Antibody (YA5422) is a mouse-derived and non-conjugated monoclonal antibody, targeting to Cytochrome C. It can be applicated for WB, ICC/IF, IHC-P assays, in the background of human, mouse, rat, chicken.

CYCS is an electron carrier protein. The oxidized form of the cytochrome c heme group accepts an electron from the cytochrome c1 subunit of cytochrome reductase and transfers it to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Additionally, CYCS plays a role in apoptosis. Inhibition of anti-apoptotic members or activation of pro-apoptotic members of the Bcl-2 family alters mitochondrial membrane permeability, leading to the release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers caspase-9 activation, which then accelerates apoptosis by activating other caspases. by similar: electron transport chain function and apoptosis regulation mechanisms.

P99999

Observed band size: 14 kDa

affinity chromatography.

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human, Mouse, Rat, Chicken

WB: 1:1000-5000; IHC: 1:500-1000; ICC/IF: 1:200

WB, ICC/IF, IHC-P

Liquid

Supplied in PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

Recombinant Protein of CYCS