Cripto1/CRIPTO Antibody (YA4799)

Cripto1/CRIPTO Antibody (YA4799) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Cripto1/CRIPTO.

Cripto is a GPI-anchored cell membrane protein involved in the Nodal signaling pathway. Cell-associated CRIPTO functions as a Nodal coreceptor in cis. Shedding of CRIPTO by TMEM8A modulates Nodal signaling by enabling soluble CRIPTO to act as a Nodal coreceptor on other cells (by similar: PubMed:27881714). It may also play a role in determining epiblastic cells that subsequently give rise to the mesoderm (by similar: PubMed:11909953).

P13385

Predicted band size: 21 kDa;

affinity purified.

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human

WB: 1:500-1:2000; ELISA: 1:10000

WB, ELISA

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

Purified recombinant fragment of human Cripto expressed in E. Coli.