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  5. CLASP1 Antibody (YA2133)

CLASP1 Antibody (YA2133)

Cat. No.: HY-P82388
User Guide for Antibodies Technical Support

CLASP1 Antibody (YA2133) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2133), targeting CLASP1, with a predicted molecular weight of 169 kDa (observed band size: 169 kDa). CLASP1 Antibody (YA2133) can be used for WB, IHC-P, ICC/IF, FC experiment in mouse, rat, human background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

CLASP1 Antibody (YA2133) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2133), targeting CLASP1, with a predicted molecular weight of 169 kDa (observed band size: 169 kDa). CLASP1 Antibody (YA2133) can be used for WB, IHC-P, ICC/IF, FC experiment in mouse, rat, human background.
Background

CLASP1 is a microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. It is involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN) and required for the polarization of cytoplasmic microtubule arrays in migrating cells towards the leading edge. CLASP1 may act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated, at least in part, by phosphatidylinositol 3-kinase signaling. By similar mechanism, CLASP1 also performs a stabilizing function at the kinetochore, which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
Gene ID
SwissProt ID
Synonyms
CLASP1; KIAA0622; MAST1; CLIP-associating protein 1; Cytoplasmic linker-associated protein 1; Multiple asters homolog 1; Protein Orbit homolog 1; hOrbit1
Molecular Weight

Predicted band size: 169 kDa; Observed band size: 169 kDa
Purity

Affinity Chromatography
Conjugation

Non-conjugated
Modification

Unmodified
Research Field

Cell Biology
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Mouse, Rat, Human
Dilution Ratio

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;FC: 1/50-1/100
Application

WB, IHC-P, ICC/IF, FC
Appearance

Liquid
Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

A synthesized peptide derived from human CLASP1
Database

Entrez Gene: 23332 Human ; 76707 Mouse ; 304740 Rat

SwissProt: Q7Z460 Human ; Q80TV8 Mouse ;

OMIM: 605852 Human

Documentation
User Guide for Antibodies (1077 KB)

CLASP1 Antibody (YA2133) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CLASP1 Antibody (YA2133)
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