CIRBP Antibody (YA2506)

CIRBP Antibody (YA2506) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2506), targeting CIRBP, with a predicted molecular weight of 19 kDa (observed band size: 19 kDa). CIRBP Antibody (YA2506) can be used for WB, IHC-P, IP experiment in human background.

Cold-Inducible RNA Binding Protein (CIRBP) is a crucial player in the cellular response to genotoxic stress, exerting a protective role by stabilizing transcripts of genes associated with cell survival. As a translational activator, CIRBP is involved in the cold-induced suppression of cell proliferation and binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts like RPA2 and TXN. It acts as a translational repressor, promoting the assembly of stress granules (SGs) when overexpressed. Additionally, CIRBP interacts with EIF4G1 and associates with ribosomes, emphasizing its multifaceted involvement in cellular stress responses and RNA processing (

Q14011

Predicted band size: 19 kDa; Observed band size: 19 kDa

Affinity Purified

Non-conjugated

Unmodified

Epigenetics and Nuclear Signaling

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

WB: 1/500-1/1000;IHC: 1/50-1/100;IP: 1/20

WB, IHC-P, IP

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

Recombinant protein of human CIRBP