2. Antibodies
  3. Primary Antibodies
  4. Polyclonal Antibodies
  5. CHRNA9 Antibody

CHRNA9 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to CHRNA9.

For research use only. We do not sell to patients.

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10 μL In-stock
50 μL In-stock
100 μL In-stock
250 μL   Get quote  
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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

CHRNA9 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to CHRNA9.
Background

CHRNA9 is a component of neuronal acetylcholine receptors (nAChRs), which function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotransmitter receptors formed by a collection of nAChR subunits known to mediate synaptic transmission in the nervous system and the neuromuscular junction. Each nAChR subunit confers differential attributes to channel properties, including activation, deactivation and desensitization kinetics, pH sensitivity, cation permeability, and binding to allosteric modulators. CHRNA9 can form either homopentamers or heteropentamers with CHRNA10 and is expressed in the inner ear, sympathetic neurons, and other non-neuronal cells such as skin keratinocytes and lymphocytes. The nAChR formed by CHRNA9:CHRNA10 mediates central nervous system control of auditory and vestibular sensory processing. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current that hyperpolarizes the cell membrane. In the ear, CHRNA9 mediates synaptic transmission between efferent olivocochlear fibers and hair cells of the cochlea, which may reduce basilar membrane motion, alter auditory nerve fiber activity, and narrow the dynamic hearing range, potentially protecting against acoustic trauma (by similarity). Additionally, CHRNA9 may regulate keratinocyte adhesion.
Tag

Free
Gene ID
SwissProt ID
Molecular Weight

Predicted band size: 55 kDa; Observed band size: 55 kDa
Conjugation

Non-conjugated
Modification

Unmodified
Product Categories

Primary Antibody; Rabbit Polyclonal Antibody
Clonality

Polyclonal
Host

Rabbit
Reactivity

Human, Rat
Dilution Ratio

WB: 1:500-1:1000 ;IHC: 1:50-1:100
Application

WB, IHC-P
Appearance

Liquid
Formulation

Supplied in pH 7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage & Stability

Stored at -20°C.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

Synthetic peptide corresponding to human CHRNA9.The exact sequence is proprietary to MCE.
Database

Entrez Gene: 55584 Human ; 231252 Mouse ; 65024 Rat

SwissProt: Q9UGM1 Human ; P43144 Rat

OMIM: 605116 Human

Documentation
SDS (251 KB)

COA (190 KB)

User Guide for Antibodies (1077 KB)

CHRNA9 Antibody Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Product Name:
CHRNA9 Antibody
Cat. No.:
HY-P81023
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English - EN (251 KB)

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