CDC42 Antibody (YA3440)

Cat. No.: HY-P83703: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

CDC42 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 21 kDa, targeting to CDC42. It can be used for WB、IHC-P、FC assays with tag free, in the background of Human, Mouse,Rat.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

CDC42 Antibody (YA3440) Featured Recommendations:

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
Technical Parameters
Properties
Documentation

Description	CDC42 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 21 kDa, targeting to CDC42. It can be used for WB、IHC-P、FC assays with tag free, in the background of Human, Mouse,Rat.
Background	CDC42, a plasma membrane-associated small GTPase, dynamically transitions between an active GTP-bound state and an inactive GDP-bound state, modulating diverse cellular responses by interacting with various effector proteins. Notably, CDC42 is intricately involved in processes such as epithelial cell polarization, where it plays a critical role in regulating spindle microtubule attachment to kinetochores before chromosome congression in metaphase. Additionally, CDC42 influences cell migration and is pivotal for the extension and maintenance of filopodia, slender actin-rich projections, in neurons. In the context of neuronal plasticity, it participates in CaMKII-mediated signaling, impacting dendritic spine structural plasticity and contributing to long-term synaptic changes. Moreover, CDC42 is essential for the formation of spines in specific neuronal cell types, such as Purkinje cells and hippocampal neurons, through interactions with DOCK10 and DOCK11. In podocytes, it facilitates the formation of filopodia and podosomes upon activation by DOCK11. Furthermore, CDC42 plays a crucial role in the orchestration of F-actin cytoskeleton dynamics during phagocytosis, contributing to the formation of phagocytic cups. This multifaceted engagement underscores the versatility of CDC42 in regulating various cellular functions.
Gene ID	998 [NCBI]
SwissProt ID	P60953
Synonyms	CDC42
Molecular Weight	Predicted band size: 21 kDa; Observed band size: 21 kDa
Purity	Protein A affinity purified.
Conjugation	Non-conjugated
Modification	Unmodified
RRID	AB_3676586
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Monoclonal, Recombinant
Host	Rabbit
Reactivity	Human, Mouse, Rat
Dilution Ratio	WB: 1:1,000;IF-Cell: 1:500;FC: 1:,000;
Application	WB, ICC/IF, FC
Positive Control	HepG2 cell lysate, MCF7 cell lysate, NIH/3T3 cell lysate, C2C12 cell lysate, C6 cell lysate, Mouse brain tissue lysate, Rat brain tissue lysate, HepG2, NIH/3T3, C6, HepG2
Appearance	Liquid
Formulation	Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Immunogen	Recombinant protein within Human CDC42 aa 30-191 / 191.
Database	Entrez Gene: 998 Human ; 12540 Mouse ; 64465 Rat SwissProt: P60953 Human ; P60766 Mouse ; Q8CFN2 Rat OMIM: 616737 Human
Documentation	Select Batch: Data Sheet (235 KB) SDS (251 KB) COA (190 KB) User Guide for Antibodies (1077 KB)

CDC42 Antibody (YA3440) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Product Name

Requested Quantity *

Applicant Name *

Salutation

Email Address *

Phone Number *

Department

Organization Name *

City

State

Country or Region *

Remarks

Product Name

Lot #

Applicant Name *

Country or Region *

Email Address *

Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

CDC42 Antibody (YA3440)

CDC42 Antibody (YA3440) Featured Recommendations:

Biological Activity

Technical Parameters

Properties

Documentation

CDC42 Antibody (YA3440) Related Classifications

Your Recently Viewed Products:

Request for HNMR Report

SAFETY DATA SHEET (SDS)

Request for HNMR Report