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  4. CCT2 Antibody (YA2320)

CCT2 Antibody (YA2320)

Cat. No.: HY-P82575
User Guide for Antibodies Technical Support

CCT2 Antibody (YA2320) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2320), targeting CCT2, with a predicted molecular weight of 57 kDa (observed band size: 57 kDa). CCT2 Antibody (YA2320) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

CCT2 Antibody (YA2320) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2320), targeting CCT2, with a predicted molecular weight of 57 kDa (observed band size: 57 kDa). CCT2 Antibody (YA2320) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

Background

CCT2 operates as an integral component of the chaperonin-containing T-complex (TRiC), a sophisticated molecular chaperone complex pivotal for protein folding through ATP hydrolysis. This versatile complex plays a crucial role in mediating the folding of various proteins, including WRAP53/TCAB1, thus influencing telomere maintenance. Furthermore, as part of the TRiC complex, CCT2 may contribute to the assembly of the BBSome, a complex essential for ciliogenesis that regulates the transport of vesicles to cilia. The TRiC complex's involvement in the folding of actin and tubulin underscores its multifaceted functions in cellular processes (Probable). Structurally, CCT2 is a key constituent of the TRiC complex, a heterooligomeric assembly characterized by two stacked rings, each measuring 12 to 16 nm in diameter. Beyond its structural role, CCT2 engages in interactions with various proteins, including PACRG, FLCN, and DLEC1, further highlighting its significance in diverse cellular processes.

Gene ID
SwissProt ID
Synonyms
CCT2; 99D8.1; CCTB; T-complex protein 1 subunit beta; TCP-1-beta; CCT-beta
Molecular Weight

Predicted band size: 57 kDa; Observed band size: 57 kDa

Purity

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Signal Transduction

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

Dilution Ratio

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/50;FC: 1/50-1/100

Application

WB, IHC-P, ICC/IF, IP, FC

Appearance

Liquid

Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthesized peptide derived from human TCP1 beta

Database
Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CCT2 Antibody (YA2320)
Cat. No.:
HY-P82575
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