Caldesmon Antibody (YA4187)

Cat. No.: HY-P84490: Data Sheet User Guide for Antibodies
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Caldesmon Antibody (YA4187) is a mouse-derived and non-conjugated IgG1 antibody, targeting to CALD1. It can be applicated for WB, IHC-P, FC, ELISA assays, in the background of human, mouse, rat.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
Technical Parameters
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Documentation

Description	Caldesmon Antibody (YA4187) is a mouse-derived and non-conjugated IgG1 antibody, targeting to CALD1. It can be applicated for WB, IHC-P, FC, ELISA assays, in the background of human, mouse, rat.
Background	CALD1 is an actin- and myosin-binding protein implicated in regulating actomyosin interactions in smooth muscle and nonmuscle cells (potentially acting as a bridge between myosin and actin filaments). It stimulates tropomyosin binding to actin, thereby stabilizing actin filament structure. In muscle tissues, CALD1 inhibits actomyosin ATPase activity by binding to F-actin, with this inhibition attenuated by calcium-calmodulin and enhanced by tropomyosin. It interacts with actin, myosin, two tropomyosin molecules, and calmodulin. Additionally, CALD1 plays essential roles in cellular mitosis, receptor capping, and Schwann cell migration during peripheral nerve regeneration (by similar).
Gene ID	800 [NCBI]
SwissProt ID	Q05682
Synonyms	CDM; HCAD; LCAD; H-CAD; L-CAD; NAG22
Molecular Weight	Predicted band size: 93 kDa; Observed band size: 70-75 kDa
Purity	affinity purified.
Conjugation	Non-conjugated
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Host	Mouse
Reactivity	Human, Mouse, Rat
Dilution Ratio	WB: 1/500-1/2000; IHC: 1/200-1/1000; FC: 1/200-1/400; ELISA: 1/10000
Application	WB, IHC-P, FC, ELISA
Appearance	Liquid
Formulation	Supplied in PBS with 0.05% sodium azide
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG1
Immunogen	Purified recombinant fragment of human CALD1 (AA: 26-207) expressed in E. Coli.
Documentation	Data Sheet (234 KB) User Guide for Antibodies (1077 KB)

Caldesmon Antibody (YA4187) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Caldesmon Antibody (YA4187)

Biological Activity

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Caldesmon Antibody (YA4187) Related Classifications

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