ATP4B Antibody (YA2972)

ATP4B Antibody (YA2972) is a non-conjugated IgG antibody, targeting ATP4B, with a predicted molecular weight of 33 kDa (observed band size: 55 kDa). ATP4B Antibody (YA2972) can be used for WB experiment in human background.

ATP4B is the beta subunit of the gastric H(+)/K(+) ATPase pump, which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. It plays a structural and regulatory role in the assembly and membrane targeting of a functionally active pump (By similarity). During a transport cycle, the transfer of an H(+) ion across the membrane is coupled to ATP hydrolysis and involves transient phosphorylation of the alpha subunit, shifting the pump conformation from the inward-facing (E1) to the outward-facing (E2) state. ATP4B interacts with the phosphorylation domain of the alpha subunit, acting as a ratchet to stabilize the lumenal-open E2 conformation and prevent the reverse reaction of the transport cycle (By similarity).

P51164

Predicted band size: 33 kDa; Observed band size: 55 kDa

Affinity Purified

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

WB: 1/500-1/1000

WB

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human ATP4B