ApoO Antibody (YA4735)

ApoO Antibody (YA4735) is a mouse-derived and non-conjugated monoclonal antibody, targeting to ApoO. It can be applicated for WB, IHC-P, ICC/IF, ELISA assays, in the background of human, mouse.

ApoO is a component of the MICOS complex, a large protein complex in the mitochondrial inner membrane that plays critical roles in maintaining crista junctions, inner membrane architecture, and forming contact sites with the outer membrane. It is essential for crista junction formation and mitochondrial function. ApoO can promote cardiac lipotoxicity by enhancing mitochondrial respiration and fatty acid metabolism in cardiac myoblasts. Additionally, it facilitates cholesterol efflux from macrophage cells and is detected in HDL, LDL, and VLDL. ApoO is secreted via a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, likely as a VLDL-associated protein that is later transferred to HDL. by similar functions include its role in cholesterol metabolism and lipoprotein transport.

Q9BUR5

Predicted band size: 22 kDa;

affinity purified.

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human, Mouse

WB: 1:500-1:2000; IHC: 1:200-1:1000; ELISA: 1:10000; ICC/IF: 1:50-200

WB, IHC-P, ICC/IF, ELISA

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

Purified recombinant fragment of ApoO expressed in E. Coli.