ApoD Antibody (YA2584)

ApoD Antibody (YA2584) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2584), targeting ApoD, with a predicted molecular weight of 21 kDa (observed band size: 28 kDa). ApoD Antibody (YA2584) can be used for WB, IHC-P experiment in human background.

The IL-1RA/IL-1RN Protein operates as a potent anti-inflammatory antagonist within the interleukin-1 family, specifically targeting proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. This protein serves as a crucial safeguard against immune dysregulation and uncontrolled systemic inflammation triggered by IL1, responding to various innate stimulatory agents, including pathogens. Its ability to modulate the inflammatory response highlights its significance in potential therapeutic interventions aimed at managing inflammatory disorders and maintaining immune balance. Shifting focus to the Alpha 1-Microglobulin Protein, it emerges as a multifunctional antioxidant and tissue repair agent, exhibiting reductase, heme-binding, and radical-scavenging activities. Operating in both intravascular and extravascular spaces, this protein plays a pivotal role in red cell homeostasis, protecting against heme-induced cell damage and mitigating oxidative stress. Its diverse functions span from preventing hemolysis in red blood cells to reducing extracellular methemoglobin and inhibiting oxidation of low-density lipoprotein particles during acute inflammation. Moreover, Alpha 1-Microglobulin safeguards against oxidation products in the extracellular matrix and cell membranes, contributing to cellular and extracellular matrix integrity. Within the intracellular milieu, it maintains mitochondrial redox homeostasis, offering protection against heme-induced oxidative damage and facilitating correct protein folding in the endoplasmic reticulum. Additionally, this protein exhibits antiprotease activity, inhibiting key proteases involved in inflammatory and cytotoxic responses, and plays a crucial role in extracellular matrix remodeling and cell adhesion.

P05090

Predicted band size: 21 kDa; Observed band size: 28 kDa

Affinity Purified

Non-conjugated

Unmodified

Neuroscience

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

WB: 1/500-1/1000;IHC: 1/50-1/100

WB, IHC-P

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human ApoD